Medical Entonox gas

Medical Entonox gas (or Entonox painkiller gas) is a pre-mixed and standard mixture of oxygen gas (O2) and nitrous oxide (N2O) gas that is mixed with identical concentrations (50%+50%) and supplied in cylinders. The composition of this medical gas has a pain-relieving effect (analgesic), and reduces anxiety, while keeping the patient conscious; So, it is used in many short-term painful procedures in hospitals, emergency departments, dental clinics, skin care clinics, and beauty centers. The presence of 50% oxygen in Entonox composition provides a higher oxygen concentration than ambient air and helps in keeping the patient's blood oxygen-saturated.

Applications of medical Entonox gas

Entonox is a pre-mixed gas mixture that is used in many medical and paraclinical actions where the patient needs immediate and controlled relief. Some of the most important applications of medical Entonox gas are:

Natural and Painless Childbirth

One of the famous applications of Entonox gas is in the Obstetrics and Gynecology Department to reduce natural childbirth pain. Mother inhales this gas via special mouth masks under the supervision of the treatment team to reduce the pain when painful contractions occur, even though there is no need for general anesthesia. The gas starts to take effect quickly, and its effect diminishes suddenly when the flow is cut.

Dentistry

In dentistry, eunoto is a sedation and painkiller method, especially when you face anxious patients, children, or some people with less pain and stress tolerance. The mixture of 50% nitrous oxide and 50% oxygen help the patient to be calm and have better cooperation with the dentist, while he/she is caseous. In some cases, according to the protocol, medical nitrous oxide gas is solely used to kill the pain and sedate.

Skin and Beauty

In some skin and beauty procedures that are rather painful (such as laser or non-invasive superficial treatments), Entonox can be used as a short-term painkiller option, under the supervision of a doctor and along with other local anesthesia methods. In many of these procedures, medical O2 and in some skin and burn treatments, medical liquid nitrogen are used along with Entonox.

Changing Burn Wound Dressings

Changing burn wound dressings, especially in kids and patients with extensive burns, can be very painful. Entonox can be used in these cases to reduce the pain and anxiety when the dressing is being changed and help the treatment team to do the procedure with increased tolerance of the patient.

Painful Injections, Especially to Kids

In painful injections or some procedures like catheter, difficult blood draw, or some outpatient actions for kids, controlled usage of Entonox can reduce the pain and fear, and create a more tolerable experience for the kid and his/her parents.

Endoscopy and Colonoscopy

In some medical centers, Entonox is a part of the pain relief protocol in endoscopy and colonoscopy to reduce the pain and discomfort during gastrointestinal examinations, while maintaining the ability to cooperate and change body position as directed by the physician.

Severe Pains and Short-Term Procedures

Entonex can be used as a short-term, controllable painkiller to manage acute pain, such as pain from cancer, traumatic injuries, stitching, or suture removal from sensitive and painful areas; provided that it is used in a therapeutic environment and under the supervision of an expert team. In many of these applications, Entonox is used along with other gases such as medical oxygen and other medical gases, as a part of the standard equipment of the operating room in hospitals and clinics.

Advantages of using Medical Entonox gas:

• Fast and short-term pain-killing effect; it takes effect shortly after inhalation and has a quick recovery after discontinuation
• Maintaining the patient's alertness and responsiveness, conscious sedation is not followed in many procedures.
• Contains 50% oxygen, providing a better oxygen saturation compared to breathing ambient air.
• Suitable for a wide range of short-term procedures: childbirth, dentistry, burn treatment, endoscopy, suturing, and more.
• Allows patient-controlled inhalation in many protocols (especially with a Demand Valve system) under supervision of the medical team

Limitations of Medical Entonox Gas

Despite its relative safety, the use of Entonox — like any medical gas — can be hazardous if professional guidelines are not followed. For example:
• Possibility of mild side effects such as nausea, vomiting, dizziness, lightheadedness, or short-term drowsiness
• In vulnerable people, the risk of decreased level of consciousness when it is used inappropriately or longer than the prescribed time
• In patients with severe pulmonary diseases or in places with insufficient ventilation, the risk of CO2 retention or disorders in breathing pattern is probable when it is not monitored well
• Since nitrous oxide emits fast, its usage may be forbidden or limited in some cases (closed cavities that contain gas, pneumothorax, intestinal obstruction, …) and needs careful evaluation by a doctor
Therefore, Entonox should only be used according to treatment protocols and under the supervision of a doctor and trained personnel, and with standard equipment; any arbitrary usage outside the therapeutic environment can be dangerous for patients and even the personnel.

Accessories and Technical Considerations of Medical Entonox Gas

The Entonox gas is supplied as a pre-mixed gas (50% oxygen+50% nitrous oxide) in cylinders, and it needs standard medical gas equipment for safe and efficient usage; this equipment is:
• Special regulator and manometer for Entonox or nitrous oxide-oxygen, along with safety systems and a pressure-limiting device
• Gas delivery systems such as face masks, mouthpieces, or circuits equipped with a demand valve for controlled inhalation
• Standard houses and connections with colored tags and suitable index pins to prevent mistakes when connecting the cylinder
• Expiratory evacuation and collection systems (scavenging systems) in the operating room and clamp units for reducing personnel exposure to nitrous oxide
From the technical point of view, it is necessary to follow the manufacturer’s instructions about the storage pressure and temperature of the cylinders to keep the gas composition identical all the time and prevent the malfunctioning of the cylinder equipment.

Entonox Gas Cylinder and Tank

Medical Entonox gas is supplied in cylinders; these cylinders are generally labeled and have different colors to be recognizable from other gases. The type, composition, working pressure, and safety cautions are pasted on them. Based on the needs of the treatment center, various capacities can be provided, such as:
• 5 Liter Entonox cylinder
• 10 Liter Entonox cylinder
• 20 Liter Entonox cylinder
• 40 Liter Entonox cylinder
Choosing a suitable capacity depends on the number of procedures and the consumption rate.

Safety, Storage, and Transportation of Entonox Gas

Keeping the cylinders vertically: Cylinders must be kept in a vertical position and be restrained by a clamp and chains to prevent fall or impact.
A suitably ventilated environment: sufficient ventilation is necessary to reduce possible gas accumulation, especially in small rooms without windows.
Away from heat and flame: keep Entonox cylinders away from heat sources, direct sunlight, and hot lates.
Safe transportation: Use a special trolley or cart to carry cylinders and prevent rolling or pulling them on the floor.
Periodic inspection: Checking the date of hydrostatic tests, the integrity of the valve and body, and the clarity of the labels should be done regularly.
Furthermore, educating the personnel about opening and closing the valves, correct utilization of the regulator, and emergency condition management (such as gas leakage or cylinder fall) is an important part of safety considerations when working with Entonox gas.

Price and Terms of Purchase for Medical Entonox Gas

Medical Entonox gas price depends on several main parameters, including cylinder capacity.
To inquire about the price, you need to determine the required number and volume of the cylinder so we can offer a more precise price.

Purchase of Medical Entonox Gas

The quality, composition homogeneity of 50% oxygen and 50% nitrous oxide, standardization of cylinder and continuous supply are important when purchasing medical Entonox gas, which directly affect the services and patient safety. Akhavan Kalantari Company, with years of experience in providing medical gases, can supply medical Entonox gas for treatment centers with the highest quality in standard cylinders.
Contact our sales team to inquire about the price, order registration, and scheduling a regular supply of Entonox gas. Furthermore, if you center requires other medical or industrial gases such as medical oxygen, nitrogen, liquid nitrogen, carbon dioxide, … it is possible for you to purchase a complete package of medical and industrial gases from Akhavan Kalantari Company as a reputable and reliable company.

Entonox (gas) N2O + O2 
Purity Grade Type
99.95 3.5 Medical
99.999 5 Laboratory

Akhavan Kalantari Company is the supplier of Entonox gas with the highest purity.

Please contact our experts for more information about purchasing, pricing, and order placement methods

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